BDBM24701 4-aminopyrazolylpyrimidine analogue, 10g::5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-phenylethyl]pyrimidine-2,4-diamine

SMILES C[C@H](Nc1ncc(Br)c(Nc2cc(n[nH]2)C2CC2)n1)c1ccccc1

InChI Key InChIKey=UEBUEWAMMXNGMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24701   

LigandPNGBDBM24701(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed