BDBM246691 US9550763, Compound I-344

SMILES Clc1ccc(Cn2c(=O)c(c[nH]\c2=N/c2ccc(Oc3ccon3)cc2)C(=O)NCC#C)cc1

InChI Key InChIKey=ILVFICZNLKUUTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246691   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM246691(US9550763, Compound I-344)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
Go to US Patent