BDBM24664 2-(1H-imidazol-4-yl)benzene-1,3-diol::2-(1H-imidazol-4-yl)benzene-1,3-diol, 11

SMILES Oc1cccc(O)c1-c1c[nH]cn1

InChI Key InChIKey=VMNQZTQDHXFNPD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24664   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24664(2-(1H-imidazol-4-yl)benzene-1,3-diol | 2-(1H-imida...)
Affinity DataIC50: 5.30E+3nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24664(2-(1H-imidazol-4-yl)benzene-1,3-diol | 2-(1H-imida...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24664(2-(1H-imidazol-4-yl)benzene-1,3-diol | 2-(1H-imida...)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed