BDBM246501 (4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-4,6-heptadien-3-one (21)

SMILES COc1cc(\C=C\C=C\C(=O)CCc2ccc(O)cc2)ccc1O

InChI Key InChIKey=VJBQUBGTUNBGDY-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246501   

TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246501((4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy...)
Affinity DataIC50: 3.08E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246501((4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy...)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM246501((4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy...)
Affinity DataKi:  2.17E+3nM ΔG°:  -8.03kcal/mole IC50: 1.11E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed