BDBM246500 (4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-one (20)

SMILES Oc1ccc(CCC(=O)\C=C\C=C\c2ccc(O)cc2)cc1

InChI Key InChIKey=QIROPQQWKBMABC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246500   

TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246500((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246500((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...)
Affinity DataIC50: 3.39E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM246500((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...)
Affinity DataKi:  1.92E+3nM ΔG°:  -8.11kcal/mole IC50: 9.12E+3nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed