BDBM246493 3,5-Dimethoxy-2,7-phenanthrenediol (11)

SMILES COc1cc2c(ccc3cc(O)cc(OC)c23)cc1O

InChI Key InChIKey=YKFWCNBTQYCJQV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246493   

TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246493(3,5-Dimethoxy-2,7-phenanthrenediol (11))
Affinity DataIC50: 9.98E+3nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246493(3,5-Dimethoxy-2,7-phenanthrenediol (11))
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM246493(3,5-Dimethoxy-2,7-phenanthrenediol (11))
Affinity DataKi:  2.67E+3nM ΔG°:  -7.90kcal/mole IC50: 1.27E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed