BDBM246487 Batatasin III (4)::US20240398793, Compound 8

SMILES COc1cc(O)cc(CCc2cccc(O)c2)c1

InChI Key InChIKey=VYQXIUVIYICVCM-UHFFFAOYSA-N

Data  1 KI  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 246487   

LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataEC50:  6.72E+4nMAssay Description:Modulation of GABAA alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataEC50:  6.73E+4nMAssay Description:Modulation of GABAA alpha3beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataEC50:  8.08E+4nMAssay Description:Modulation of GABAA alpha2beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataIC50: 4.09E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataIC50: 4.09E+5nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Celltaxis

US Patent
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataIC50: 1.70E+3nMAssay Description:The hydrolase-homogeneous time resolved fluorescence assay is a two-step assay that measures the hydrolysis of LTA4 to LTB4 by analyzing the amount o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataKi:  6.79E+3nM ΔG°:  -7.33kcal/mole IC50: 3.23E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed