BDBM246485 Tristin (1)

SMILES COc1cc(CCc2cc(O)cc(O)c2)ccc1O

InChI Key InChIKey=KPFFMALTIRFAHW-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 246485   

TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM246485(Tristin (1))
Affinity DataKi:  2.75E+3nM ΔG°:  -7.89kcal/mole IC50: 1.35E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed