BDBM24592 (2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5-en-2-yl 2-formamidoacetate::Orlistat derivative, 17g

SMILES CCCCCC[C@H]1[C@H](C[C@@H](CC\C=C\C)OC(=O)CNC=O)OC1=O

InChI Key InChIKey=YEWKKVDDJYHYSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24592   

TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandPNGBDBM24592((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 6.24E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed