BDBM24553 3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl]methyl}sulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10r

SMILES OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(Cl)c(c2)C(F)(F)F)c1

InChI Key InChIKey=FLSQMBDKSLKOPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24553   

LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.06E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 7.42E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 6.31E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed