BDBM24494 N,N-diethyl-7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)thieno[3,2-b]pyridine-2-carboxamide::thieno[3,2-b]pyridine-based inhibitor, 8d

SMILES CCN(CC)C(=O)c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1

InChI Key InChIKey=NXEYJEPOEMMBPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24494   

TargetHepatocyte growth factor receptor(Human)
Methylgene

LigandPNGBDBM24494(N,N-diethyl-7-(2-fluoro-4-{[(1-phenylacetamido)met...)
Affinity DataIC50: 114nMpH: 7.5 T: 2°CAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
LigandPNGBDBM24494(N,N-diethyl-7-(2-fluoro-4-{[(1-phenylacetamido)met...)
Affinity DataIC50: 386nMAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

LigandPNGBDBM24494(N,N-diethyl-7-(2-fluoro-4-{[(1-phenylacetamido)met...)
Affinity DataIC50: 114nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed