BDBM24486 3-(3-fluoro-4-{thieno[3,2-b]pyridin-7-yloxy}phenyl)-1-(2-phenylacetyl)thiourea::thieno[3,2-b]pyridine-based inhibitor, 6a

SMILES Fc1cc(NC(=S)NC(=O)Cc2ccccc2)ccc1Oc1ccnc2ccsc12

InChI Key InChIKey=DNBVMOXDARBOEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24486   

TargetHepatocyte growth factor receptor(Human)
Methylgene

LigandPNGBDBM24486(3-(3-fluoro-4-{thieno[3,2-b]pyridin-7-yloxy}phenyl...)
Affinity DataIC50: 116nMpH: 7.5 T: 2°CAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
LigandPNGBDBM24486(3-(3-fluoro-4-{thieno[3,2-b]pyridin-7-yloxy}phenyl...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

LigandPNGBDBM24486(3-(3-fluoro-4-{thieno[3,2-b]pyridin-7-yloxy}phenyl...)
Affinity DataIC50: 116nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed