BDBM24471 4-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline::Triazolopyridazine, 10a

SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(F)cc3)ccnc2c1

InChI Key InChIKey=HZBHYZXMLODTCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24471   

LigandPNGBDBM24471(4-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyrid...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. Mole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
LigandPNGBDBM24471(4-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyrid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed