BDBM244375 US9550763, Compound I-127

SMILES C[C@@H](Cn1c(=O)cc(Nc2ccc(Oc3cccc(n3)C#N)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O

InChI Key InChIKey=IQDDWAADKRIYMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244375   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM244375(US9550763, Compound I-127)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
Go to US Patent