BDBM244092 US9428478, TG6-251-1

SMILES CC(C)Oc1ccc(cc1)N1CCN(CC1)C(=O)c1nc2cc(ccc2[nH]1)C(N)=O

InChI Key InChIKey=SVEMPGFHAVLXDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244092   

TargetCytochrome b-245 heavy chain(Human)
Emory University

US Patent
LigandPNGBDBM244092(US9428478, TG6-251-1)
Affinity DataIC50: 1.00E+9nMAssay Description:Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Emory University

US Patent
LigandPNGBDBM244092(US9428478, TG6-251-1)
Affinity DataIC50: 2.00E+10nMAssay Description:Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent