BDBM244061 US9428478, TG6-144-2

SMILES CC(=O)c1ccc(NCC(=O)N2CCN(CC2)c2ccc(N)cc2)cc1

InChI Key InChIKey=KYVDSTYQWDSAQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244061   

TargetCytochrome b-245 heavy chain(Human)
Emory University

US Patent
LigandPNGBDBM244061(US9428478, TG6-144-2)
Affinity DataIC50: 2.00E+8nMAssay Description:Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Emory University

US Patent
LigandPNGBDBM244061(US9428478, TG6-144-2)
Affinity DataIC50: 2.00E+8nMAssay Description:Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent