BDBM244010 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-isopropoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin 6 yl)pyrimidine-2,4-diamine::US10053458, 70

SMILES CC(C)Oc1cc2C(C)NCCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=VELNKDUOTZKDQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244010   

TargetALK tyrosine kinase receptor [L1196M](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM244010(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM244010(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)
Affinity DataIC50: 10nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent