BDBM24359 N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)phenyl]octanediamide::Triazole Ligand, 14c

SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cnnn1-c1ccccc1

InChI Key InChIKey=WHOVTJMDYILSIW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24359   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 33.4nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 167nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 7.70nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 942nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 24.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

LigandPNGBDBM24359(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50: 7.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed