BDBM24357 N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hydroxyoctanediamide::Triazole Ligand, 14a

SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cnnn1Cc1ccccc1

InChI Key InChIKey=UQIMEFHEVVKGJC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24357   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 18.6nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 112nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 4.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 433nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 19.2nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

LigandPNGBDBM24357(N-[3-(1-benzyl-1H-1,2,3-triazol-5-yl)phenyl]-N'-hy...)
Affinity DataIC50: 3.30nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed