BDBM24348 N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,3-triazol-4-yl}phenyl)-N'-hydroxyoctanediamide::Triazole Ligand, 6d

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cn(CC(O)c2cccc(Br)c2)nn1

InChI Key InChIKey=KYKYBDPQRYYVLN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24348   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 69.2nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 143nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 25.3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 3.13E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 86.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50: 4.40nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed