BDBM24345 N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hydroxyoctanediamide::Triazole Ligand, 6a

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cn(Cc2ccccc2)nn1

InChI Key InChIKey=VPPFVJQPLWFTFT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 24345   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

LigandPNGBDBM24345(N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...)
Affinity DataIC50: 113nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

LigandPNGBDBM24345(N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...)
Affinity DataIC50: 679nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

LigandPNGBDBM24345(N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...)
Affinity DataIC50: 3.97E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

LigandPNGBDBM24345(N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...)
Affinity DataIC50: 188nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

LigandPNGBDBM24345(N-[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...)
Affinity DataIC50: 4.80nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed