BDBM243448 US9427428, 12::US9433609, 12

SMILES COC(=O)NC(C1CCOCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)C(NC(=O)OC)C1CCOCC1

InChI Key InChIKey=IUCSKNNJNLCPSX-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 243448   

TargetGenome polyprotein [810-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.0800nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [810-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.110nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-3011](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.268nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1973-2419,Y2165H](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.275nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1657-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.0800nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1657-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.110nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1657-3011](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.268nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1973-2419,Y2165H](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243448(US9433609, 12 | US9427428, 12)
Affinity DataEC50:  0.275nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent