BDBM243441 US9427428, 2

SMILES CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC

InChI Key InChIKey=PEOWHPQZIHJCOF-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 243441   

TargetGenome polyprotein [810-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  0.540nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [810-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  0.909nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [1973-2419,L2000T](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  9.05nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [1973-2419,R2002H](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  2.69nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [1973-2419,L2003F](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  1.81nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [1973-2419,L2003V](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  1.38nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
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TargetGenome polyprotein [1973-2419,Y2165H](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  2.88nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1973-2419,Y2165C](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243441(US9427428, 2)
Affinity DataEC50:  0.655nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent