BDBM243331 US10053454, Example 75

SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1cc(OC(F)(F)F)cc2n(c3c(cc(cc3c12)-c1c(C)noc1C)C(N)=O)S(=O)(=O)C1CC1

InChI Key InChIKey=RVEAIANDFHLXDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243331   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243331(US10053454, Example 75)
Affinity DataIC50: 500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
Go to US Patent