BDBM2432 6-benzyl-4-hydroxy-2-mercapto-5-methylpyrimidine::6-benzyl-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one::DABO Thio Analogue 5a

SMILES Cc1c(Cc2ccccc2)[nH]c(=S)[nH]c1=O

InChI Key InChIKey=LMYJDTWTSBWPEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2432   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2432(6-benzyl-4-hydroxy-2-mercapto-5-methylpyrimidine |...)
Affinity DataIC50: 1.00E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2004
Entry Details Article
PubMed