BDBM24305 Letrozole derivative, 34::{2-chloro-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]phenyl} sulfamate

SMILES NS(=O)(=O)Oc1ccc(cc1Cl)C(c1ccc(cc1)C#N)n1cncn1

InChI Key InChIKey=KFYVHFCQRAUDFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24305   

TargetAromatase(Human)
University of Bath

LigandPNGBDBM24305({2-chloro-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24305({2-chloro-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 920nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed