BDBM24128 4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide::CHEMBL380367::tetrahydroisoquinoline (THIQ), 32

SMILES Cc1ccc2c(c1C)CN(C[C@@H]2c3cccc(c3)O)C(=O)N(C)C

InChI Key InChIKey=HPVCRUIDFODATB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24128   

TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24128(CHEMBL380367 | 4-(3-hydroxyphenyl)-N,N,7,8-tetrame...)
Affinity DataIC50: 306nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)