BDBM241145 US9409895, 55::US9630945, 55

SMILES Clc1cc(Cl)cc(OCC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)c1

InChI Key InChIKey=GOPMVDAVXQIINY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241145   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241145(US9409895, 55 | US9630945, 55)
Affinity DataIC50: 154nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241145(US9409895, 55 | US9630945, 55)
Affinity DataIC50: 154nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent