BDBM241142 US9409895, 52::US9630945, 52

SMILES Clc1cc(Cl)cc(COC(=O)NC2CCN(CC2)C(=O)CCCCc2c[nH]nn2)c1

InChI Key InChIKey=GIHUJSZUVQGKBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241142   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241142(US9409895, 52 | US9630945, 52)
Affinity DataIC50: 42nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241142(US9409895, 52 | US9630945, 52)
Affinity DataIC50: 42nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent