BDBM241128 US9409895, 39::US9630945, 39

SMILES Clc1ccc(\C=C\C(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)c(Cl)c1

InChI Key InChIKey=GPXXBCUCRBYWJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241128   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241128(US9409895, 39 | US9630945, 39)
Affinity DataIC50: 77nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241128(US9409895, 39 | US9630945, 39)
Affinity DataIC50: 77nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent