BDBM241116 US9409895, 27::US9630945, 27

SMILES Clc1cc(Cl)cc(COC(=O)N2CCN(CCNC(=O)c3c[nH]c(=O)o3)CC2)c1

InChI Key InChIKey=IKEDPSMWEXUYKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 241116   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241116(US9409895, 27 | US9630945, 27)
Affinity DataIC50: 375nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241116(US9409895, 27 | US9630945, 27)
Affinity DataIC50: 375nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241116(US9409895, 27 | US9630945, 27)
Affinity DataIC50: 370nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed