BDBM241107 US9409895, 18::US9630945, 18

SMILES CN(C1CCN(CC1)C(=O)OCc1cc(Cl)cc(Cl)c1)C(=O)CCCc1c[nH]nn1

InChI Key InChIKey=FEDLFXXCRJIDTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 241107   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241107(US9409895, 18 | US9630945, 18)
Affinity DataIC50: 94nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241107(US9409895, 18 | US9630945, 18)
Affinity DataIC50: 94nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM241107(US9409895, 18 | US9630945, 18)
Affinity DataIC50: 93nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed