BDBM24110 2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-amine::CHEMBL381599::tetrahydroisoquinoline (THIQ), 15

SMILES Cc1ccc2C(CN(CCN)Cc2c1C)c1ccccc1

InChI Key InChIKey=UQSPLCZWTHEZMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24110   

TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24110(2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 2.27E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24110(2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed