BDBM24107 2-ethyl-7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline::CHEMBL207973::tetrahydroisoquinoline (THIQ), 12

SMILES CCN1CC(c2ccccc2)c2ccc(C)c(C)c2C1

InChI Key InChIKey=KXHNOIFAYOEWOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24107   

TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24107(CHEMBL207973 | 2-ethyl-7,8-dimethyl-4-phenyl-1,2,3...)
Affinity DataIC50: 2.52E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24107(CHEMBL207973 | 2-ethyl-7,8-dimethyl-4-phenyl-1,2,3...)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed