BDBM240926 US9409892, 21

SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1

InChI Key InChIKey=YLAYKCQTUJKINN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 240926   

TargetProlyl hydroxylase EGLN2(Human)
Fibrogen

US Patent
LigandPNGBDBM240926(US9409892, 21)
Affinity DataIC50: 240nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetEgl nine homolog 1(Human)
Fibrogen

US Patent
LigandPNGBDBM240926(US9409892, 21)
Affinity DataIC50: 9.40E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetEgl nine homolog 1(Human)
Fibrogen

US Patent
LigandPNGBDBM240926(US9409892, 21)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Fibrogen

US Patent
LigandPNGBDBM240926(US9409892, 21)
Affinity DataIC50: 240nMAssay Description:Inhibition of HIF-PHD1 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed