BDBM240858 US9394331, 120::US9394331, 121

SMILES COc1nc(N)nc2n(cnc12)C1O[C@H](COP(=O)(N[C@@H](C)C(=O)OCC(C)(C)C)Oc2ccccc2)[C@@H](O)[C@]11CCO1

InChI Key InChIKey=QBBUGVSYQKSNSK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240858   

TargetGenome polyprotein [2420-3010](HCV)
Gilead Pharmasset

US Patent
LigandPNGBDBM240858(US9394331, 121 | US9394331, 120)
Affinity DataEC50:  390nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [2420-3010](HCV)
Gilead Pharmasset

US Patent
LigandPNGBDBM240858(US9394331, 121 | US9394331, 120)
Affinity DataEC50:  9.31E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent