BDBM240825 (S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanamido)-N-hydroxy-3-methylbutanamide hydrochloride (7b)

SMILES CC(C)[C@H](NC(=O)[C@H](O)[C@@H](N)c1ccccc1)C(=O)NO

InChI Key InChIKey=NGQQZCRHCINBBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240825   

TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM240825((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)
Affinity DataIC50: 7.70E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Pig)
Shandong University

LigandPNGBDBM240825((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)
Affinity DataIC50: 1.28E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed