BDBM240807 N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6-yl)-3-(piperidin-1-yl)propanamide (3h)

SMILES O=C(CCN1CCCCC1)Nc1ccc2nc([nH]c(=O)c2c1)-c1cc2ccccc2[nH]1

InChI Key InChIKey=JOCZIAQMXYHQML-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 240807   

TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 21.0nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Sun Yat-Sen University

LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 7.32E+3nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylcholine chloride as substrate incubated measured after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM240807(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 7.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed