BDBM240744 US9422273, 12a

SMILES Fc1ccc(CCC(=O)NS(=O)(=O)C(F)(F)F)c(CN2CCC[C@H]2c2nc(co2)C(=O)NCCCCC2CCCCC2)c1

InChI Key InChIKey=BJUUQOLZOPQZKM-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 240744   

TargetProstaglandin F2-alpha receptor(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  350nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstaglandin D2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstaglandin E2 receptor EP1 subtype(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  47nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  6.40E+3nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  82nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  38nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetProstacyclin receptor(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50:  550nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
Go to US Patent