BDBM240737 US9422263, 14

SMILES Cc1n[nH]c2cc(F)c(cc12)C1C(C#N)=C(NC(C(F)F)=C1C#N)C(F)F

InChI Key InChIKey=WOWAGKXGSRDYJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240737   

TargetHepatocyte growth factor receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM240737(US9422263, 14)
Affinity DataIC50: 26nMpH: 7.0 T: 2°CAssay Description:Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetHepatocyte growth factor receptor [960-1390](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM240737(US9422263, 14)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The N-terminally His6-tagged recombinant kinase domain of the human c-Met (amino acids 960-1390), expressed in insect cells (SF21) and purified by Ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent