BDBM24036 (2R)-3-phenyl-2-[(4-phenylbenzene)sulfonamido]propanoic acid::CHEMBL49411::biphenylsulfonamide carboxylate, 13

SMILES OC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=JBYHBQIDTNHWJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24036   

LigandPNGBDBM24036(CHEMBL49411 | (2R)-3-phenyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 4.30E+3nMpH: 7.5 T: 2°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2008
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM24036(CHEMBL49411 | (2R)-3-phenyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM24036(CHEMBL49411 | (2R)-3-phenyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against Matrix metalloprotease-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM24036(CHEMBL49411 | (2R)-3-phenyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloprotease-2 MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed