BDBM24035 (2R)-2-[(4-phenylbenzene)sulfonamido]pentanedioic acid::JMC517486 Compound 11c::biphenylsulfonamide carboxylate, 12::cid_644601

SMILES OC(=O)CC[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=IQGHPUPMOUUHPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24035   

LigandPNGBDBM24035(JMC517486 Compound 11c | (2R)-2-[(4-phenylbenzene)...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2008
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM24035(JMC517486 Compound 11c | (2R)-2-[(4-phenylbenzene)...)
Affinity DataIC50: 1.72E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM24035(JMC517486 Compound 11c | (2R)-2-[(4-phenylbenzene)...)
Affinity DataIC50: 2.08E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay