BDBM23989 1,2,3,4-tetrahydronaphthalen-2-one::CHEMBL191664::dihydro-naphthalenone, 4e::dihydronaphthalenone

SMILES O=C1CCc2ccccc2C1

InChI Key InChIKey=KCKZIWSINLBROE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 23989   

TargetCytosol aminopeptidase(Bovine)
Enscmu

LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Enscmu

LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Enscmu

LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human CYP2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCytochrome P450 2A5(Mouse)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A5(Mouse)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: 9.71E+3nMAssay Description:Inhibition of mouse CYP2A5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed