BDBM23936 1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene::trans-Stilbene Derivative, 4i

SMILES FC(F)(F)c1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1

InChI Key InChIKey=ISPYNXGXZRLLHM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23936   

TargetAryl hydrocarbon receptor(Rabbit)
Institut Claudius Regaud

LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  0.200nM ΔG°:  -12.3kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to AhR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Institut Claudius Regaud

LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi: >1.00E+5nMAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2008
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  2.00E+8nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article