BDBM23917 3-amidinophenylalanine deriv., 59::3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl}phenyl)propanamide::CHEMBL379194

SMILES NCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key InChIKey=CEVNTYRWLYLNLF-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 23917   

TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  6.60nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.40E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  3.60E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.10E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.70E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM23917(3-amino-N-(3-{[(2S)-1-[4-(2-aminoethyl)piperidin-1...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed