BDBM239039 US10028934, Compound 28::US10478423, Cpd. 28::US9408850, 28::US9597317, 28

SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CC(C1)N1CCCC1

InChI Key InChIKey=SWXOORVKAHJWLM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 239039   

TargetReceptor-type tyrosine-protein kinase FLT3 [564-993](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 136nMpH: 7.9 T: 2°CAssay Description:The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was pre activat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit [544-976](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 306nMpH: 7.9Assay Description:The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) was pre ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 136nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 306nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 136nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 306nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 136nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 306nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
Go to US Patent