BDBM239007 US9403846, 21

SMILES NC1=N[C@]2(CO[C@H](C[C@H]2CS1)[C@@H]1CCCO1)c1ccc(F)cc1F

InChI Key InChIKey=AYIXLNDRJRRIAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239007   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239007(US9403846, 21)
Affinity DataIC50: 302nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent