BDBM238988 US9403846, 5

SMILES COC[C@H]1SC(N)=N[C@]2(CO[C@H](C[C@@H]12)C1CC1)c1ccc(F)cc1F

InChI Key InChIKey=VDVXUIFRNRFJLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238988   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238988(US9403846, 5)
Affinity DataIC50: 1.41E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent