BDBM238346 US9388165, 2

SMILES Cc1ccc(cc1NC(=O)c1cccc2c(NC(C)(C)C)nccc12)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=MMANGHIETAOBGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238346   

LigandPNGBDBM238346(US9388165, 2)
Affinity DataIC50: 11nMAssay Description:The compounds prepared in Examples were tested for inhibitory activities against three subtypes of RAF, i.e. RAF1 Y340D Y341D, BRAF normal type and B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent