BDBM238343 US9394275, I-67

SMILES CC(Cc1ccc(CNC(=O)Cc2ccc(cc2)N(C)C(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2-c2ccccc2)cc1)NCCc1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=QFMKACVXSOIJAJ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238343   

TargetBeta-2 adrenergic receptor(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM238343(US9394275, I-67)
Affinity DataEC50:  1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetMuscarinic acetylcholine receptor M3(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM238343(US9394275, I-67)
Affinity DataKi:  0.100nM ΔG°:  -14.2kcal/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent